Technical Webinar – Tandem LIBS and LA-ICP-MS for Biological Samples
Elemental Imaging from Tissues to Single Cells and Organelles
Join us for a special two-part webinar featuring expert researchers from the University of Surrey (UK) and King’s College London as they present their latest innovations in laser-based elemental imaging of biological samples. From tissue-level mapping to live single-cell and organelle analysis, this session will explore how tandem LIBS and LA-ICP-MS techniques are advancing our understanding of biological systems and enhancing approaches to drug delivery.
Date: Jun 18, 2025
Time: 8:30 AM to 10 AM PST
Location: Live Online Webinar
Presentation 1
Element Imaging of Biological Samples with Tandem LIBS and LA-ICP-MS
Tips for Optimization and Normalization – Our Experience at Surrey
Speaker: Dr. Mónica Felipe-Sotelo, University of Surrey
Dr. Felipe-Sotelo presents practical strategies for leveraging the complementary strengths of LIBS and LA-ICP-MS in biological tissue analysis. This session will focus on optimizing laser parameters and implementing innovative normalization approaches using LIBS signals to enhance LA-ICP-MS image quality and data reliability.
You’ll learn:
- How LIBS enables detection of bulk matrix elements (e.g., H, C, N, O)
- How LA-ICP-MS achieves trace-level sensitivity with spatial precision
- Best practices for optimizing LIBS and LA parameters in tissue samples
- Strategies for quantifying both exogenous and endogenous elements
About the Speaker:
Dr. Mónica Felipe-Sotelo is a Senior Lecturer in Radiochemistry and Analytical Chemistry at the University of Surrey’s School of Chemistry and Chemical Engineering. Her research bridges elemental analysis method development and its application to environmental and biological challenges. She also leads Surrey’s atomic spectroscopy and elemental analysis facility, equipped with tandem LA/LIBS and QQQ-ICP-MS instruments funded by UKRI. Dr. Felipe-Sotelo has authored over 50 peer-reviewed publications and is an expert in chemometrics, experimental design, and atomic spectroscopy.
Presentation 2
Can You Find It There? Pushing the Barriers of Single Cell & Organelle Analysis with LA-ICP-MS
Speaker: Dr. Claire Davison, King’s College London
Dr. Davison presents a groundbreaking workflow that combines capillary sampling with LA-ICP-MS to detect metals in live cells and isolated organelles. The method is demonstrated using thallium exposure—a radiopharmaceutical metal—offering new insights into elemental uptake at the subcellular level.
What you’ll discover:
- The importance of single-cell and subcellular LA-ICP-MS analysis for understanding metal function and improving drug delivery
- How capillary sampling enhances LA-ICP-MS by enabling detection of metals in subcellular compartments of living cells
- Insights into metal uptake kinetics in the context of radiopharmaceutical therapy
About the Speaker:
Dr. Claire Davison is a Postdoctoral Research Associate at King’s College London, specializing in subcellular mass spectrometry. She completed her BSc in Chemistry with Forensic Investigation at the University of Surrey and began her PhD in 2021 under the guidance of Dr. Felipe-Sotelo, Professor Bailey, and Dr. Beste. Her doctoral research focused on developing analytical techniques for trace metal detection in single cells and organelles—particularly in the context of Mycobacterium tuberculosis infection. Her work pushes the boundaries of high-resolution bioimaging and metal–host interaction studies at the microscale.
Register Now to reserve your seat and explore two powerful case studies advancing elemental bioanalysis.
